IgE testing must be accurate and precise. Immuno Labs performs IgE panels on the best laboratory equipment available. We conduct our testing using fluorescent enzyme immunoassay (FEIA) that measures the concentration of circulating allergen-specific IgE antibodies in serum. This helps to identify specific allergic reactions and, when coupled with a history of exposure and allergic symptom development, may help identify allergic triggers. The testing process begins with the specific antigen being bound to a three-dimensional hydrophilic cellulose polymer, which can bind significantly more allergen than older disk methods. This substrate allows for increased antigen binding and improved sensitivity. Patient serum is mixed with the antigen-bound substrate, permitting antigen-specific patient IgE to complex. Next, the complexed substrate is mixed with an enzyme–IgE conjugate forming a secondary immune complex. Subsequently, a fluorogenic material is applied to the secondary immune complex, which results in the formation of a fluorescent secondary immune complex. Using a fluorometer, the fluorescence is read, and the quantification correlates with the quantity of patient IgE. Immuno Labs IgE testing demonstrates a very high specificity, high efficiency, and high sensitivity. The testing instrumentation we use has over 4,000 scientific articles, which shows its clinical value and why it is championed as “The Gold Standard” for in vitro IgE testing.